Insulin Resistance, Associated Subclinical Inflammation and Cardiovascular Risks

نویسنده

  • Mario Ciampolini
چکیده

People cannot share subjective sensations with others as they do with sounds and figures. Subjective sensations guide the intake. In this chapter, subjective sensations of hunger that induce intake, become objective (verifiable by others, reproducible and comparable) by the association with measurements of blood glucose concentration (BG). This is possible after about two weeks of training with BG measurements. Subjective sensations become thus a meal by meal information tool on energy balance. Respecting the arousal of the validated sensation before any intake was useful to treat infants with chronic non-specific diarrhea (Ciampolini et al. 1990). In a health policy for cardiovascular risk prevention, for a suppression of subclinical inflammation and for a decrease or maintenance of a stable body weight, treating functional intestinal disorders means treating a reversible condition like insulin resistance to prevent irreversible events. Functional intestinal disorders are also capable to give valid motivation to patients for training (see further “Training to...”).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mechanism of subclinical hypothyroidism accelerating endothelial dysfunction (Review)

The association between subclinical hypothyroidism (SH) and cardiovascular disease has received increasing attention in recent years. The predisposition of patients with SH to endothelial dysfunction, an early sign of atherosclerosis, has been observed. This predisposition may be partially explained by the factors also found in patients with SH, including changes in lipid profile, low grade chr...

متن کامل

Inflammation Markers and Metabolic Characteristics of Subjects With 1-h Plasma Glucose Levels

OBJECTIVE To assess the association of 1-h plasma glucose (1hPG) and inflammation with normal glucose tolerance (NGT) and pre-diabetes. RESEARCH DESIGN AND METHODS A cohort of 1,062 subjects was enrolled. After oral glucose load (oral glucose tolerance test), we compared subjects with NGT and pre-diabetes above and below the 1hPG cut point (155 mg/dl). Fibrinogen and leukocytes count (white b...

متن کامل

C-reactive protein is independently associated with fasting insulin in nondiabetic women.

OBJECTIVE Insulin resistance is associated with chronic subclinical inflammation, and both conditions are linked with increased risk for type 2 diabetes mellitus and atherothrombotic cardiovascular disease. METHODS AND RESULTS In a cross-sectional study conducted among participants in the Women's Health Study, an ongoing US primary prevention trial of cardiovascular disease and cancer, we eva...

متن کامل

Role of omentin-1 and C-reactive protein in obese subjects with subclinical inflammation

Background While chronic subclinical inflammation is now considered to be a predisposing risk factor of cardiovascular diseases, the extent by which adipokines induce metabolic abnormalities in humans is not fully resolved. The purpose of this study was to examine the relationship between insulin resistance and serum inflammatory markers in obese subjects. Methods One hundred and five subject...

متن کامل

Obesity and renal disease: not all fat is created equal and not all obesity is harmful to the kidneys.

The prevalence of obesity is increasing worldwide and contributes to many health problems, including kidney disease. Unexpectedly, 10-30% of obese individuals are apparently not at increased risk of metabolic diseases, e.g. type 2 diabetes, cardiovascular disease and risk of renal disease. Their phenotype is labeled 'metabolically healthy obesity'. In the search for mechanisms explaining this u...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012